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Zoloft dosage depends on the condition being treatedZoloft may interact with nonsteroidal anti-inflammatory drugsNSAIDsother medicines that make you sleepysuch as cold or allergy medicinesedativesnarcoticssleeping pillsmuscle relaxersand medicines for seizures or anxietycimetidinedigoxinfentanyllinezolidlithiumStJohn’s worttramadol5-hydroxytryptophanvalproateblood thinnerscough and cold medicinesother antidepressantsheart rhythm medicationsor migraine headache medicinesTell your doctor all medications and supplements you useZoloft use during pregnancy may lead to adverse effects in the newbornIt is unknown if Zoloft passes into breast milkConsult your doctor before breastfeedingIn some patientsif Zoloft is discontinued abruptlywithdrawal side effects include abdominal crampsflu-like symptomsfatigueand memory impairment.
A study conducted in juvenile rats at clinically relevant doses showed delay in sexual maturationbut there was no effect on fertility in either males or females.
Based on pharmacokinetic studiesno dosage adjustment of ZOLOFT is necessary when used in combination with cimetidineAdditionallyno dosage adjustment is required for diazepamlithiumatenololtolbutamidedigoxinand drugs metabolized by CYP3A4when ZOLOFT is administered concomitantlySee CLINICAL PHARMACOLOGY
Call your healthcare provider right away if you have any of the following symptomsor call 911 if an emergencyespecially if they are newworseor worry you:
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