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Increased prothrombin timewith or without clinical bleedinghas been reported when cefixime is administered concomitantly.

Reconstitution/preparation techniques The manufacturer’s product information should be consulted.

Cephalosporinsincluding Supraxmay be associated with a fall in prothrombin activityThose at risk include patients with renal or hepatic impairmentor poor nutritional stateas well as patients receiving a protracted course of antimicrobial therapyand patients previously stabilized on anticoagulant therapyProthrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicated.

Safety and effectiveness of cefixime in children aged less than six months old have not been establishedThe incidence of gastrointestinal adverse reactionsincluding diarrhea and loose stoolsin the pediatric patients receiving the suspensionwas comparable to the incidence seen in adult patients receiving tablets.

Strep throat is a bacterial infection of the throatSigns and symptoms of strep throat include headachenauseavomitingsore throatand fever.

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cefixime is an antibiotic.